HitPredict

Interactor 1: RPN11 (P41878)
26S proteasome regulatory subunit rpn11 (Protein pad1)
Gene: RPN11

Interactor 2: RPN1 (P87048)
26S proteasome regulatory subunit rpn1 (19S regulatory cap region of 26S protease subunit 2) (Proteasome non-ATPase subunit mts4)
Gene: RPN1

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.76	1.00	0.873

Property	Details
Experiments	9727008, 28784663, 9822592, 20838651
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	JAB~PC_rep
Common GO terms	GO:0000502 - proteasome complex GO:0005634 - nucleus GO:0034399 - nuclear periphery GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 308 Sp			1 891
+	Hs
		130871 PSDE_HUMAN (19-308): 2.23e-105: 311: 70.35		PSMD2_HUMAN (1-885): 0: 1224: 47.36
+	At
		1339597 PSDE_ARATH (1-308): 1.67e-110: 324: 69.81		PSD2A_ARATH (3-885): 0: 1148: 46.77
+	Hs
		849192 PSMD7_HUMAN (27-307): 4.23e-59: 193: 19.80		PSMD2_HUMAN (1-885): 0: 1224: 47.36
+	Dm
		1358676 PSDE_DROME (1-308): 7.51e-111: 325: 67.86		Q9VW54_DROME (41-885): 0: 1064: 46.89
+	At
		1320083 PSD7B_ARATH (15-307): 3.7e-57: 188: 18.09		PSD2A_ARATH (3-885): 0: 1148: 46.77
+	At
		188942 PSD7A_ARATH (15-307): 4.68e-57: 188: 17.76		PSD2A_ARATH (3-885): 0: 1148: 46.77
+	Dm
		640795 PSMD7_DROME (26-307): 6.44e-60: 196: 19.05		Q9VW54_DROME (41-885): 0: 1064: 46.89
+	Sc
		753858 RPN11_YEAST (1-308): 6.26e-93: 279: 64.29		RPN1_YEAST (50-885): 0: 901: 39.42
+	Sc
		753971 RPN8_YEAST (28-184): 4.36e-32: 123: 26.38		RPN1_YEAST (50-885): 0: 901: 39.42
+	Hs
		131053 PSDE_HUMAN (19-308): 2.23e-105: 311: 70.35		PSMD1_HUMAN (141-826): 6.09e-171: 522: 19.43
+	Dm
		1358666 PSDE_DROME (1-308): 7.51e-111: 325: 67.86		PSMD1_DROME (370-819): 2.85e-141: 447: 21.91
+	Sp
		251846 RPN11_SCHPO (1-308): 4.2e-107: 316: 100.00		RPN2_SCHPO (350-820): 9.6e-136: 431: 22.31
+	Sc
		693323 RPN11_YEAST (1-308): 6.26e-93: 279: 64.29		RPN2_YEAST (60-822): 4.16e-145: 455: 18.37
+	Hs
		849257 PSMD7_HUMAN (27-307): 4.23e-59: 193: 19.80		PSMD1_HUMAN (141-826): 6.09e-171: 522: 19.43
+	Dm
		640780 PSMD7_DROME (26-307): 6.44e-60: 196: 19.05		PSMD1_DROME (370-819): 2.85e-141: 447: 21.91
+	Hs
		696 PSMD7_HUMAN (27-307): 4.23e-59: 193: 19.80		A0A087WW66_HUMAN (141-826): 6.93e-140: 440: 18.87
+	Sc
		693372 RPN8_YEAST (28-184): 4.36e-32: 123: 26.38		RPN2_YEAST (60-822): 4.16e-145: 455: 18.37