HitPredict

Interactor 1: RPN11 (P41878)
26S proteasome regulatory subunit rpn11 (Protein pad1)
Gene: RPN11

Interactor 2: PSB4 (Q09720)
Probable proteasome subunit beta type-4
Gene: SPAC31A2.04c

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	20838651
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 308 Sp			1 194
+	Dm
		1358671 PSDE_DROME (1-308): 7.51e-111: 325: 67.86		Q9VJJ0_DROME (1-193): 1.15e-67: 207: 45.08
+	Dm
		1178949 PSDE_DROME (1-308): 7.51e-111: 325: 67.86		Q7K148_DROME (2-193): 2.48e-66: 206: 19.79
+	Sp
		675389 RPN11_SCHPO (1-308): 4.2e-107: 316: 100.00		PSB5_SCHPO (3-189): 1.18e-67: 209: 19.25
+	Dm
		1278634 PSDE_DROME (1-308): 7.51e-111: 325: 67.86		PSA5_DROME (3-187): 5.9e-64: 199: 18.56
+	Dm
		771306 PSDE_DROME (1-308): 7.51e-111: 325: 67.86		PSA2_DROME (4-193): 5.84e-64: 198: 14.58
+	Dm
		1358675 PSDE_DROME (1-308): 7.51e-111: 325: 67.86		Q9VUJ1_DROME (4-193): 5.21e-63: 197: 16.84
+	Sp
		195130 RPN11_SCHPO (1-308): 4.2e-107: 316: 100.00		PSB1_SCHPO (3-191): 3.77e-65: 201: 19.05
+	Sp
		784769 RPN11_SCHPO (1-308): 4.2e-107: 316: 100.00		PSB2_SCHPO (3-190): 1.58e-64: 201: 19.68
+	Sp
		784767 RPN11_SCHPO (1-308): 4.2e-107: 316: 100.00		PSA3_SCHPO (4-187): 5.21e-64: 199: 15.59
+	Hs
		130757 PSDE_HUMAN (19-308): 2.23e-105: 311: 70.35		PSB5_HUMAN (2-193): 1.75e-65: 203: 18.75
+	Sp
		784781 RPN11_SCHPO (1-308): 4.2e-107: 316: 100.00		PSA5_SCHPO (3-188): 1.17e-63: 198: 15.98
+	Hs
		130747 PSDE_HUMAN (19-308): 2.23e-105: 311: 70.35		PSA2_HUMAN (4-192): 1.94e-64: 199: 15.71
+	Hs
		130749 PSDE_HUMAN (19-308): 2.23e-105: 311: 70.35		PSA4_HUMAN (3-194): 2.95e-63: 198: 14.80
+	Hs
		130798 PSDE_HUMAN (19-308): 2.23e-105: 311: 70.35		PSB2_HUMAN (1-193): 6.76e-62: 192: 45.60
+	Hs
		130736 PSDE_HUMAN (19-308): 2.23e-105: 311: 70.35		PSB1_HUMAN (3-191): 3.42e-33: 120: 23.23
+	Dm
		771410 PSDE_DROME (1-308): 7.51e-111: 325: 67.86		PSB1_DROME (3-189): 4.47e-28: 106: 22.73
+	Sp
		784776 RPN11_SCHPO (1-308): 4.2e-107: 316: 100.00		PSB6_SCHPO (3-189): 1.51e-23: 95: 19.61
+	Mm
		192889 PSDE_MOUSE (19-308): 2.23e-105: 311: 70.35		PSB4_MOUSE (3-189): 2.25e-18: 81.9: 18.42
+	Hs
		130755 PSDE_HUMAN (19-308): 2.23e-105: 311: 70.35		PSB4_HUMAN (3-189): 3.81e-18: 81.1: 18.42
+	Hs
		130797 PSDE_HUMAN (19-308): 2.23e-105: 311: 70.35		PSB3_HUMAN (4-190): 5e-17: 77.3: 18.09