HitPredict

Interactor 1: RPN11 (P41878)
26S proteasome regulatory subunit rpn11 (Protein pad1)
Gene: RPN11

Interactor 2: PSA4 (Q10329)
Probable proteasome subunit alpha type-4
Gene: pre6

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	20133687, 20838651
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0034399 - nuclear periphery GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 308 Sp			1 259
+	Dm
		1278634 PSDE_DROME (1-308): 7.51e-111: 325: 67.86		PSA5_DROME (2-233): 1.76e-93: 277: 34.44
+	Hs
		130644 PSDE_HUMAN (19-308): 2.23e-105: 311: 70.35		PSA7_HUMAN (4-230): 8.52e-97: 285: 54.59
+	Dm
		611650 PSDE_DROME (1-308): 7.51e-111: 325: 67.86		PSA71_DROME (2-229): 8.62e-91: 270: 52.61
+	Sp
		784781 RPN11_SCHPO (1-308): 4.2e-107: 316: 100.00		PSA5_SCHPO (2-237): 5.79e-94: 278: 32.79
+	Hs
		130746 PSDE_HUMAN (19-308): 2.23e-105: 311: 70.35		PSA1_HUMAN (2-259): 1.01e-93: 278: 27.27
+	Hs
		130754 PSDE_HUMAN (19-308): 2.23e-105: 311: 70.35		PSA5_HUMAN (2-232): 7.74e-94: 277: 34.03
+	Sp
		784767 RPN11_SCHPO (1-308): 4.2e-107: 316: 100.00		PSA3_SCHPO (1-238): 2.11e-89: 266: 32.26
+	Hs
		130824 PSDE_HUMAN (19-308): 2.23e-105: 311: 70.35		PSA6_HUMAN (2-236): 7.16e-90: 267: 29.88
+	Sc
		771370 RPN11_YEAST (1-308): 6.26e-93: 279: 64.29		PSA4_YEAST (1-232): 5.22e-93: 275: 58.48
+	Sc
		689189 RPN11_YEAST (1-308): 6.26e-93: 279: 64.29		PSA5_YEAST (2-245): 1.62e-91: 272: 32.54
+	Hs
		156334 CSN5_HUMAN (28-304): 3.44e-73: 230: 30.10		PSA7_HUMAN (4-230): 8.52e-97: 285: 54.59
+	Hs
		637505 CSN5_HUMAN (28-304): 3.44e-73: 230: 30.10		PSA1_HUMAN (2-259): 1.01e-93: 278: 27.27
+	Hs
		893720 CSN5_HUMAN (28-304): 3.44e-73: 230: 30.10		PSA6_HUMAN (2-236): 7.16e-90: 267: 29.88
+	Dm
		771306 PSDE_DROME (1-308): 7.51e-111: 325: 67.86		PSA2_DROME (4-212): 3.06e-48: 161: 37.92
+	Dm
		640776 PSMD7_DROME (26-307): 6.44e-60: 196: 19.05		PSA5_DROME (2-233): 1.76e-93: 277: 34.44
+	Mm
		643130 PSMD7_MOUSE (27-307): 1.42e-59: 195: 19.80		PSA1_MOUSE (2-259): 1.99e-93: 277: 27.65
+	Sp
		293712 RPN11_SCHPO (1-308): 4.2e-107: 316: 100.00		PSA2_SCHPO (4-211): 2.04e-44: 151: 37.44
+	Dm
		611629 PSMD7_DROME (26-307): 6.44e-60: 196: 19.05		PSA71_DROME (2-229): 8.62e-91: 270: 52.61
+	Hs
		130747 PSDE_HUMAN (19-308): 2.23e-105: 311: 70.35		PSA2_HUMAN (3-210): 2.47e-45: 153: 38.10
+	Dm
		640767 PSMD7_DROME (26-307): 6.44e-60: 196: 19.05		PSA2_DROME (4-212): 3.06e-48: 161: 37.92