HitPredict

Interactor 1: YRB1 (P41920)
Ran-specific GTPase-activating protein 1 (Chromosome stability protein 20) (Perinuclear array-localized protein) (Ran-binding protein 1) (RANBP1)
Gene: YRB1

Interactor 2: IMB1 (Q06142)
Importin subunit beta-1 (Importin-95) (Karyopherin subunit beta-1) (Karyopherin-95)
Gene: KAP95

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37968396
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005643 - nuclear pore GO:0005737 - cytoplasm GO:0006606 - protein import into nucleus GO:0006607 - NLS-bearing protein import into nucleus and 1 others more... GO:0031267 - small GTPase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 201 Sc			1 861
+	Hs
		796746 RANG_HUMAN (39-197): 7.12e-48: 157: 50.31		IMB1_HUMAN (4-857): 7.07e-167: 509: 32.96
+	Hs
		834746 RBP2_HUMAN (18-200): 1.54e-43: 157: 35.33		IMB1_HUMAN (4-857): 7.07e-167: 509: 32.96
+	Hs
		483396 RGPD1_HUMAN (18-200): 2.83e-43: 156: 34.78		IMB1_HUMAN (4-857): 7.07e-167: 509: 32.96
+	Hs
		152779 RGPD8_HUMAN (18-200): 1.83e-42: 153: 34.78		IMB1_HUMAN (4-857): 7.07e-167: 509: 32.96
+	Sc
		691667 NUP2_YEAST (8-199): 8.17e-30: 117: 24.35		IMB1_YEAST (1-861): 3.78e-177: 534: 100.00
+	Hs
		1060923 RANB3_HUMAN (2-189): 2.41e-35: 132: 19.27		IMB1_HUMAN (4-857): 7.07e-167: 509: 32.96
+	Hs
		1060962 NUP50_HUMAN (5-196): 6.5e-36: 132: 22.68		IMB1_HUMAN (4-857): 7.07e-167: 509: 32.96
+	Hs
		796783 RANG_HUMAN (39-197): 7.12e-48: 157: 50.31		TNPO1_HUMAN (12-807): 1.04e-126: 404: 15.37
+	Hs
		834809 RBP2_HUMAN (18-200): 1.54e-43: 157: 35.33		TNPO1_HUMAN (12-807): 1.04e-126: 404: 15.37
+	Hs
		1273208 RGPD5_HUMAN (18-200): 2.09e-42: 153: 34.78		TNPO1_HUMAN (12-807): 1.04e-126: 404: 15.37
+	Hs
		155547 RANG_HUMAN (39-197): 7.12e-48: 157: 50.31		TNPO2_HUMAN (15-807): 3.1e-120: 387: 15.44
+	Hs
		1273239 NUP50_HUMAN (5-196): 6.5e-36: 132: 22.68		TNPO1_HUMAN (12-807): 1.04e-126: 404: 15.37
+	Xl
		1137361 Q6DCU3_XENLA (7-196): 4.54e-31: 119: 18.65		Q5U4V0_XENLA (12-807): 3.64e-124: 397: 14.94
+	Hs
		312202 RANG_HUMAN (39-197): 7.12e-48: 157: 50.31		IPO7_HUMAN (1-851): 2.31e-103: 345: 11.21
+	Sc
		687906 NUP2_YEAST (8-199): 8.17e-30: 117: 24.35		IMB3_YEAST (7-813): 1.96e-115: 379: 16.43
+	Hs
		178127 RANG_HUMAN (39-197): 7.12e-48: 157: 50.31		IPO8_HUMAN (1-860): 1.24e-95: 324: 11.86
+	Sc
		691631 NUP2_YEAST (8-199): 8.17e-30: 117: 24.35		IMB4_YEAST (5-756): 1.06e-49: 192: 14.36
+	Hs
		796779 RANG_HUMAN (39-197): 7.12e-48: 157: 50.31		IPO4_HUMAN (11-712): 9.72e-20: 96.9: 13.30
+	Hs
		127208 RANG_HUMAN (39-197): 7.12e-48: 157: 50.31		IPO5_HUMAN (4-604): 5.13e-11: 68.8: 9.23
+	Hs
		127219 RBP2_HUMAN (18-200): 1.54e-43: 157: 35.33		IPO5_HUMAN (4-604): 5.13e-11: 68.8: 9.23