Interactor 1: 14331 (P41932)
14-3-3-like protein 1 (Partitioning defective protein 5)
Gene: par-5

Interactor 2: SIR2 (Q21921)
NAD-dependent protein deacetylase sir-2.1 (EC 2.3.1.286) (Protein sir-2.1) (Regulatory protein SIR2 homolog 1)
Gene: sir-2.1

Species: Caenorhabditis elegans

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.69 0.60 0.646

The method score is based on:

Property Details
Experiments 16777605, 16860373
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0008340 - determination of adult lifespan
GO:0010468 - regulation of gene expression
GO:0051457 - maintenance of protein location in nucleus
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 248
Ce

1 607
+ Ce
+ Sc
+ Sc
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024