Interactor 1: CED9 (P41958)
Apoptosis regulator ced-9 (Cell death protein 9)
Gene: ced-9
Interactor 2: CED3 (P42573)
Cell death protein 3 (EC 3.4.22.60) (Caspase ced-3) [Cleaved into: Cell death protein 3 subunit p17; Cell death protein 3 subunit p15; Cell death protein 3 subunit p13]
Gene: ced-3
Species: Caenorhabditis elegans
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.93 | 0.90 | 0.915 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 9261161, 9384385, 9651369, 15543163, 25432023, 18776901, 9027312 |
| Identification Methods | affinity chromatography technology, enzymatic study, protease assay, anti tag coimmunoprecipitation, coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, cleavage reaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Bcl-2~CARD |
| Common GO terms | GO:0005737 - cytoplasm GO:0005739 - mitochondrion GO:0006915 - apoptotic process GO:0016020 - membrane GO:0030042 - actin filament depolymerization and 10 others more... |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
