HitPredict

Interactor 1: UHRF1 (B6CHA3)
E3 ubiquitin-protein ligase UHRF1 (EC 2.3.2.27) (Nuclear zinc finger protein Np95) (XNp95) (RING-type E3 ubiquitin transferase UHRF1) (Ubiquitin-like PHD and RING finger domain-containing protein 1) (Ubiquitin-like-containing PHD and RING finger domains protein 1)
Gene: UHRF1

Interactor 2: Q92133 (Q92133)
Histone H3
Gene: h3c8.S

Species: Xenopus laevis

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	24013172
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~ubiquitin
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 772 Xl			1 136
+	Hs
		935151 UHRF1_HUMAN (1-772): 0: 933: 65.54		H31_HUMAN (1-136): 9.92e-63: 189: 98.53
+	Hs
		1086285 UHRF1_HUMAN (1-772): 0: 933: 65.54		H31T_HUMAN (1-136): 9.38e-62: 187: 96.32
+	Hs
		952575 UHRF1_HUMAN (1-772): 0: 933: 65.54		H33_HUMAN (1-136): 6.98e-62: 187: 96.32
+	Hs
		1174637 UHRF1_HUMAN (1-772): 0: 933: 65.54		H32_HUMAN (1-136): 1.59e-61: 186: 99.27
+	Mm
		952760 UHRF1_MOUSE (1-772): 0: 911: 60.99		H33_MOUSE (1-136): 6.98e-62: 187: 96.32
+	Hs
		935136 UHRF2_HUMAN (1-772): 0: 904: 52.83		H31_HUMAN (1-136): 9.92e-63: 189: 98.53
+	Hs
		952560 UHRF2_HUMAN (1-772): 0: 904: 52.83		H33_HUMAN (1-136): 6.98e-62: 187: 96.32
+	Hs
		828355 UHRF1_HUMAN (1-772): 0: 933: 65.54		CENPA_HUMAN (9-133): 8.1e-45: 144: 50.00
+	At
		1247052 ORTH2_ARATH (264-764): 1.43e-112: 357: 27.55		CENH3_ARATH (4-134): 3.23e-42: 139: 48.12
+	At
		886462 SUVH4_ARATH (393-736): 1.52e-87: 291: 22.84		H33_ARATH (1-136): 2.07e-62: 189: 95.59
+	Hs
		934705 CHD3_HUMAN (212-500): 5.55e-52: 198: 16.10		H31_HUMAN (1-136): 9.92e-63: 189: 98.53
+	Hs
		952302 CHD3_HUMAN (212-500): 5.55e-52: 198: 16.10		H33_HUMAN (1-136): 6.98e-62: 187: 96.32
+	Hs
		935016 CHD5_HUMAN (263-500): 3.9e-49: 190: 17.79		H31_HUMAN (1-136): 9.92e-63: 189: 98.53
+	Hs
		1086233 CHD5_HUMAN (263-500): 3.9e-49: 190: 17.79		H31T_HUMAN (1-136): 9.38e-62: 187: 96.32
+	Mm
		56901 CHD5_MOUSE (263-500): 3.02e-48: 187: 17.79		H33_MOUSE (1-136): 6.98e-62: 187: 96.32
+	Hs
		828213 CHD3_HUMAN (212-500): 5.55e-52: 198: 16.10		CENPA_HUMAN (9-133): 8.1e-45: 144: 50.00
+	Dm
		332725 CHDM_DROME (263-473): 4.77e-38: 155: 18.40		H3_DROME (1-136): 1.59e-61: 186: 99.27
+	Hs
		935339 KDM5B_HUMAN (223-427): 3.49e-30: 130: 14.98		H31_HUMAN (1-136): 9.92e-63: 189: 98.53
+	Ce
		104625 LE418_CAEEL (179-497): 4.77e-40: 161: 16.10		HCP3_CAEEL (11-131): 1.1e-44: 149: 48.39
+	Sp
		457185 LID2_SCHPO (235-411): 2.33e-28: 124: 24.59		H31_SCHPO (1-136): 1.07e-59: 182: 91.18