HitPredict

Interactor 1: ACTY (P42025)
Beta-centractin (Actin-related protein 1B) (ARP1B)
Gene: ACTR1B

Interactor 2: CAPZB (P47756)
F-actin-capping protein subunit beta (CapZ beta)
Gene: CAPZB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	1.00	0.871

Property	Details
Experiments	28514442, 33961781, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Actin~F_actin_cap_B
Common GO terms	GO:0005829 - cytosol GO:0016020 - membrane GO:0070062 - extracellular exosome
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 376 Hs			1 272
+	Hs
		813298 ACTZ_HUMAN (1-376): 0: 728: 90.43		CAPZB_HUMAN (1-272): 4.35e-177: 490: 100.00
+	Hs
		813287 ACTB_HUMAN (8-376): 0: 581: 53.62		CAPZB_HUMAN (1-272): 4.35e-177: 490: 100.00
+	Hs
		813366 ACTG_HUMAN (7-376): 0: 581: 53.74		CAPZB_HUMAN (1-272): 4.35e-177: 490: 100.00
+	Hs
		813370 ACTC_HUMAN (5-376): 0: 577: 53.72		CAPZB_HUMAN (1-272): 4.35e-177: 490: 100.00
+	Dm
		820547 ACT3_DROME (8-376): 0: 575: 53.89		CAPZB_DROME (1-269): 1.72e-166: 463: 81.78