HitPredict

Interactor 1: ACTY (P42025)
Beta-centractin (Actin-related protein 1B) (ARP1B)
Gene: ACTR1B

Interactor 2: ACTG (P63261)
Actin, cytoplasmic 2 (EC 3.6.4.-) (Gamma-actin) [Cleaved into: Actin, cytoplasmic 2, N-terminally processed]
Gene: ACTG1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Actin~Actin
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane GO:0070062 - extracellular exosome
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 376 Hs			1 375
+	Hs
		785529 ACTY_HUMAN (1-376): 0: 776: 100.00		ACTC_HUMAN (2-375): 0: 595: 94.39
+	Hs
		891655 ACTZ_HUMAN (1-376): 0: 728: 90.43		ACTB_HUMAN (1-375): 0: 604: 98.93
+	Hs
		897031 ACTZ_HUMAN (1-376): 0: 728: 90.43		ACTG_HUMAN (1-375): 0: 604: 100.00
+	Hs
		897033 ACTZ_HUMAN (1-376): 0: 728: 90.43		ACTC_HUMAN (2-375): 0: 595: 94.39
+	Hs
		897029 ACTZ_HUMAN (1-376): 0: 728: 90.43		ACTA_HUMAN (2-375): 0: 594: 94.39
+	Hs
		929902 ACTG_HUMAN (7-376): 0: 581: 53.74		POTEE_HUMAN (1-375): 0: 729: 91.47
+	Dm
		361129 ACT4_DROME (8-376): 0: 603: 53.35		ACT2_DROME (2-375): 0: 598: 97.59
+	Dm
		361164 ACT4_DROME (8-376): 0: 603: 53.35		ACT5_DROME (2-375): 0: 598: 95.46
+	Dm
		361177 ACT4_DROME (8-376): 0: 603: 53.35		ACT3_DROME (2-375): 0: 596: 94.92
+	Dm
		361179 ACT4_DROME (8-376): 0: 603: 53.35		ACT6_DROME (2-375): 0: 596: 95.46
+	Sp
		501575 ACT_SCHPO (10-376): 0: 603: 52.83		ACT_SCHPO (1-375): 0: 594: 91.47
+	Sc
		887643 ACT_YEAST (10-376): 0: 602: 52.56		ACT_YEAST (1-375): 0: 592: 89.07
+	Gg
		891646 ACTB_CHICK (8-376): 0: 581: 53.62		ACTB_CHICK (1-375): 0: 604: 98.93
+	Hs
		891648 ACTB_HUMAN (8-376): 0: 581: 53.62		ACTB_HUMAN (1-375): 0: 604: 98.93
+	Hs
		891675 ACTG_HUMAN (7-376): 0: 581: 53.74		ACTB_HUMAN (1-375): 0: 604: 98.93
+	Hs
		929815 ACTG_HUMAN (7-376): 0: 581: 53.74		ACTG_HUMAN (1-375): 0: 604: 100.00
+	Hs
		929883 Q1KLZ0_HUMAN (8-376): 0: 581: 53.62		ACTG_HUMAN (1-375): 0: 604: 100.00
+	Hs
		929817 ACTG_HUMAN (7-376): 0: 581: 53.74		ACTC_HUMAN (2-375): 0: 595: 94.39
+	Hs
		929816 ACTG_HUMAN (7-376): 0: 581: 53.74		ACTH_HUMAN (2-375): 0: 592: 94.39