HitPredict

Interactor 1: ACTY (P42025)
Beta-centractin (Actin-related protein 1B) (ARP1B)
Gene: ACTR1B

Interactor 2: NGEF (Q8N5V2)
Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor)
Gene: NGEF

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 376 Hs			1 710
+	Hs
		785571 ACTY_HUMAN (1-376): 0: 776: 100.00		ECT2_HUMAN (146-681): 1.79e-88: 298: 15.87
+	Hs
		548675 ACTA_HUMAN (5-376): 0: 576: 53.46		VAV_HUMAN (152-709): 1.25e-98: 324: 15.87
+	Hs
		891981 ACTB_HUMAN (8-376): 0: 581: 53.62		FGD4_HUMAN (67-673): 1.49e-96: 316: 17.01
+	Hs
		932384 ACTC_HUMAN (5-376): 0: 577: 53.72		ECT2_HUMAN (146-681): 1.79e-88: 298: 15.87