HitPredict

Interactor 1: ACTY (P42025)
Beta-centractin (Actin-related protein 1B) (ARP1B)
Gene: ACTR1B

Interactor 2: TCPH (Q99832)
T-complex protein 1 subunit eta (TCP-1-eta) (CCT-eta) (Chaperonin containing T-complex polypeptide 1 subunit 7) (HIV-1 Nef-interacting protein) [Cleaved into: T-complex protein 1 subunit eta, N-terminally processed]
Gene: CCT7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 376 Hs			1 543
+	Hs
		897114 ACTZ_HUMAN (1-376): 0: 728: 90.43		TCPH_HUMAN (1-543): 0: 647: 100.00
+	Hs
		785522 ACTY_HUMAN (1-376): 0: 776: 100.00		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		785521 ACTY_HUMAN (1-376): 0: 776: 100.00		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		573159 ACTY_HUMAN (1-376): 0: 776: 100.00		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		826597 ACTZ_HUMAN (1-376): 0: 728: 90.43		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		821148 ACTZ_HUMAN (1-376): 0: 728: 90.43		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		573198 ACTZ_HUMAN (1-376): 0: 728: 90.43		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		929984 ACTG_HUMAN (7-376): 0: 581: 53.74		TCPH_HUMAN (1-543): 0: 647: 100.00
+	Sc
		792394 ACT_YEAST (10-376): 0: 602: 52.56		TCPH_YEAST (2-542): 0: 587: 62.45
+	Sc
		772912 ACT_YEAST (10-376): 0: 602: 52.56		TCPE_YEAST (2-526): 0: 568: 29.98
+	Hs
		826593 ACTB_HUMAN (8-376): 0: 581: 53.62		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		826609 ACTG_HUMAN (7-376): 0: 581: 53.74		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Sc
		760791 ACT_YEAST (10-376): 0: 602: 52.56		TCPG_YEAST (2-527): 0: 546: 30.68
+	Hs
		821144 ACTB_HUMAN (8-376): 0: 581: 53.62		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		821160 ACTG_HUMAN (7-376): 0: 581: 53.74		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		573194 ACTB_HUMAN (8-376): 0: 581: 53.62		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		573210 ACTG_HUMAN (7-376): 0: 581: 53.74		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		785523 ACTY_HUMAN (1-376): 0: 776: 100.00		TCPD_HUMAN (24-520): 4.05e-90: 288: 33.79
+	Hs
		843135 ACTZ_HUMAN (1-376): 0: 728: 90.43		TCPD_HUMAN (24-520): 4.05e-90: 288: 33.79
+	Hs
		843149 ACTG_HUMAN (7-376): 0: 581: 53.74		TCPD_HUMAN (24-520): 4.05e-90: 288: 33.79