Interactor 1: EZ (P42124)
Histone-lysine N-methyltransferase E(z) (EC 2.1.1.356) (Lysine N-methyltransferase 6) (Protein enhancer of zeste)
Gene: E(z)

Interactor 2: SAP18 (Q9VEX9)
Histone deacetylase complex subunit SAP18 (18 kDa Sin3-associated polypeptide) (Bicoid-interacting protein 1) (dSAP18)
Gene: Bin1

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.57 0.60 0.586

The method score is based on:

Property Details
Experiments 12039038
Identification Methods pull down, anti bait coimmunoprecipitation, molecular sieving, two hybrid
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0031507 - heterochromatin formation
GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 760
Dm

1 150
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024