HitPredict

Interactor 1: FOXK1 (P42128)
Forkhead box protein K1 (Myocyte nuclear factor) (MNF)
Gene: FOXK1

Interactor 2: SIN3B (Q62141)
Paired amphipathic helix protein Sin3b (Histone deacetylase complex subunit Sin3b) (Transcriptional corepressor Sin3b)
Gene: SIN3B

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.614

Property	Details
Experiments	22476904, 10620510
Identification Methods	pull down, two hybrid, anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0045786 - negative regulation of cell cycle GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 719 Mm			1 1098
+	Hs
		257765 FOXK2_HUMAN (91-658): 5.16e-59: 213: 53.67		SIN3B_HUMAN (14-1098): 0: 1304: 86.89
+	Hs
		952858 FOXK1_HUMAN (1-719): 9.49e-95: 311: 86.77		SIN3A_HUMAN (71-357): 1.1e-12: 74.9: 14.49
+	Sc
		609097 FKH1_YEAST (60-461): 5.32e-74: 249: 19.04		SIN3_YEAST (31-137): 1.11e-25: 117: 46.79
+	Sc
		609102 FKH2_YEAST (60-711): 2.38e-64: 231: 17.06		SIN3_YEAST (31-137): 1.11e-25: 117: 46.79
+	Hs
		964236 FOXK2_HUMAN (91-658): 5.16e-59: 213: 53.67		SIN3A_HUMAN (71-357): 1.1e-12: 74.9: 14.49