Interactor 1: STAT1 (P42224)
Signal transducer and activator of transcription 1-alpha/beta (Transcription factor ISGF-3 components p91/p84)
Gene: STAT1
Interactor 2: STAT1 (P42224)
Signal transducer and activator of transcription 1-alpha/beta (Transcription factor ISGF-3 components p91/p84)
Gene: STAT1
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.95 | 1.00 | 0.976 |
The method score is based on:
Property | Details |
---|---|
Experiments | 21914072, 16007122, 12873986, 8621447, 15284440, 9630226, 32814877, 12923054, 17374731, 23386060, 18591661, 8605877 |
Identification Methods | affinity chromatography technology, pull down, biochemical, two hybrid, x-ray crystallography, anti tag coimmunoprecipitation, cross-linking study, dynamic light scattering, cosedimentation in solution, molecular sieving and 2 others
more... |
Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | SH2~SH2, STAT_alpha~STAT_bind, STAT_alpha~STAT_int, STAT_bind~STAT_bind, STAT_int~STAT_int |
Common GO terms | GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000785 - chromatin GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000979 - RNA polymerase II core promoter sequence-specific DNA binding and 70 others more... |
Homologous interactions | 16 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024