HitPredict

Interactor 1: STAT1 (P42224)
Signal transducer and activator of transcription 1-alpha/beta (Transcription factor ISGF-3 components p91/p84)
Gene: STAT1

Interactor 2: STAT2 (P52630)
Signal transducer and activator of transcription 2 (p113)
Gene: STAT2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.988

The method score is based on:

Property Details
Experiments 31836668, 10446176, 33961781, 28514442, 8621447, 12048190, 35140242, 17923090, 10490982, 9724754, 14722125, 12954221, 17374731, 15978943, 10925286, 10523853, 20943654, 21268015, 8605877, 24065129 and 2 others

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Identification Methods affinity chromatography technology, biochemical, pull down, proximity labelling technology, anti tag coimmunoprecipitation, electrophoretic mobility supershift assay, coimmunoprecipitation, competition binding, cross-linking study, anti bait coimmunoprecipitation
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains SH2~SH2, STAT_alpha~STAT_bind, STAT_alpha~STAT_int, STAT_bind~STAT_bind, STAT_int~STAT_int
Common GO terms GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003700 - DNA-binding transcription factor activity
GO:0005634 - nucleus
and 13 others

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Homologous interactions 16

Homologous interactions

Color coding for hit scores

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Last updated: 15 Jul 2024