HitPredict

Interactor 1: STAT1 (P42224)
Signal transducer and activator of transcription 1-alpha/beta (Transcription factor ISGF-3 components p91/p84)
Gene: STAT1

Interactor 2: HDAC1 (Q13547)
Histone deacetylase 1 (HD1) (EC 3.5.1.98) (Protein deacetylase HDAC1) (EC 3.5.1.-) (Protein decrotonylase HDAC1) (EC 3.5.1.-)
Gene: HDAC1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

The method score is based on:

Property	Details
Experiments	16481475, 14645718
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000785 - chromatin GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000979 - RNA polymerase II core promoter sequence-specific DNA binding GO:0001222 - transcription corepressor binding and 12 others more... GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0006357 - regulation of transcription by RNA polymerase II GO:0019899 - enzyme binding GO:0032991 - protein-containing complex GO:0043124 - negative regulation of canonical NF-kappaB signal transduction GO:0045893 - positive regulation of DNA-templated transcription GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0048661 - positive regulation of smooth muscle cell proliferation GO:1990841 - promoter-specific chromatin binding
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1	750
Hs

1	482

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024