HitPredict

Interactor 1: STAT3 (P42227)
Signal transducer and activator of transcription 3 (Acute-phase response factor)
Gene: STAT3

Interactor 2: PO6F1 (Q07916)
POU domain, class 6, transcription factor 1 (Octamer-binding transcription factor EMB) (Transcription regulatory protein MCP-1)
Gene: Pou6f1

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	20211142
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0003677 - DNA binding GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II and 1 others more... GO:0043565 - sequence-specific DNA binding
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 770 Mm			1 301
+	Mm
		786533 STAT3_MOUSE (1-770): 0: 1050: 100.00		Q5U4D4_MOUSE (1-301): 2.77e-82: 260: 100.00
+	Hs
		540802 STAT3_HUMAN (1-770): 0: 1047: 99.87		PO2F1_HUMAN (5-293): 3.2e-59: 203: 29.87
+	Hs
		776847 STAT3_HUMAN (1-770): 0: 1047: 99.87		HESX1_HUMAN (233-298): 5.46e-21: 89.9: 33.33
+	Hs
		776700 STAT3_HUMAN (1-770): 0: 1047: 99.87		ZFHX3_HUMAN (166-299): 1.82e-10: 63.7: 19.85
+	Hs
		540811 STA5B_HUMAN (1-734): 0: 752: 30.55		PO2F1_HUMAN (5-293): 3.2e-59: 203: 29.87
+	Hs
		540804 STA5A_HUMAN (1-734): 0: 745: 30.42		PO2F1_HUMAN (5-293): 3.2e-59: 203: 29.87