Interactor 1: STAT3 (P42227)
Signal transducer and activator of transcription 3 (Acute-phase response factor)
Gene: STAT3

Interactor 2: IL17 (Q62386)
Interleukin-17A (IL-17) (IL-17A) (Cytotoxic T-lymphocyte-associated antigen 8) (CTLA-8)
Gene: Il17a

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 0.60 0.584

The method score is based on:

Property Details
Experiments 21151104, 21278738
Identification Methods anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0006954 - inflammatory response
GO:0010467 - gene expression
GO:0032731 - positive regulation of interleukin-1 beta production
GO:0032755 - positive regulation of interleukin-6 production
GO:0032760 - positive regulation of tumor necrosis factor production
and 4 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 770
Mm

1 158
+ Mm
+ Mm
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024