Interactor 1: STAT3 (P42227)
Signal transducer and activator of transcription 3 (Acute-phase response factor)
Gene: STAT3

Interactor 2: GBP5 (Q8CFB4)
Guanylate-binding protein 5 (EC 3.6.5.-) (GTP-binding protein 5) (GBP-5) (MuGBP-5) (Guanine nucleotide-binding protein 5)
Gene: GBP5

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 18065416
Identification Methods anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0006954 - inflammatory response
GO:0032731 - positive regulation of interleukin-1 beta production
GO:0042803 - protein homodimerization activity
GO:1900017 - positive regulation of cytokine production involved in inflammatory response
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 770
Mm

1 590
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024