HitPredict

Interactor 1: PP1G (P36873)
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G) (EC 3.1.3.16) (Protein phosphatase 1C catalytic subunit)
Gene: PPP1CC

Interactor 2: PPR3A (Q16821)
Protein phosphatase 1 regulatory subunit 3A (Protein phosphatase 1 glycogen-associated regulatory subunit) (Protein phosphatase type-1 glycogen targeting subunit) (RG1)
Gene: PPP1R3A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.692

Property	Details
Experiments	15016827
Identification Methods	pull down, far western blotting
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	CBM_21~Metallophos
Common GO terms	GO:0005977 - glycogen metabolic process GO:0008157 - protein phosphatase 1 binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 323 Hs			1 1122
+	Hs
		967766 PP1A_HUMAN (1-323): 0: 579: 90.66		PPR3A_HUMAN (1-1122): 0: 1723: 100.00
+	Hs
		968321 PP1B_HUMAN (1-322): 0: 560: 86.89		PPR3A_HUMAN (1-1122): 0: 1723: 100.00
+	Mm
		968192 PP1A_MOUSE (1-323): 0: 579: 90.36		PPR3A_MOUSE (1-1122): 0: 1575: 61.31
+	Hs
		786939 PP1G_HUMAN (1-323): 0: 603: 100.00		PPR3C_HUMAN (32-283): 1.18e-92: 300: 26.59
+	Hs
		968041 PP1A_HUMAN (1-323): 0: 579: 90.66		PPR3C_HUMAN (32-283): 1.18e-92: 300: 26.59
+	Hs
		968490 PP1B_HUMAN (1-322): 0: 560: 86.89		PPR3C_HUMAN (32-283): 1.18e-92: 300: 26.59
+	Hs
		342074 PP1G_HUMAN (1-323): 0: 603: 100.00		PPR3D_HUMAN (38-234): 1.15e-76: 256: 27.40
+	Hs
		786706 PP1G_HUMAN (1-323): 0: 603: 100.00		PPR3B_HUMAN (29-283): 7.72e-75: 250: 25.37
+	Hs
		342077 PP1A_HUMAN (1-323): 0: 579: 90.66		PPR3D_HUMAN (38-234): 1.15e-76: 256: 27.40
+	Hs
		967834 PP1A_HUMAN (1-323): 0: 579: 90.66		PPR3B_HUMAN (29-283): 7.72e-75: 250: 25.37
+	Mm
		59421 PP1A_MOUSE (1-323): 0: 579: 90.36		A2AJW4_MOUSE (38-234): 4.86e-69: 234: 26.44
+	Hs
		968363 PP1B_HUMAN (1-322): 0: 560: 86.89		PPR3B_HUMAN (29-283): 7.72e-75: 250: 25.37
+	Dm
		873531 PP11_DROME (5-323): 0: 569: 88.92		Q8SWT8_DROME (39-283): 2.39e-65: 226: 24.13
+	Dm
		873548 PP11_DROME (5-323): 0: 569: 88.92		Q9VUF3_DROME (39-283): 7.41e-65: 226: 24.13
+	Ce
		115256 GLC7B_CAEEL (3-323): 0: 584: 89.63		H2KYT5_CAEEL (49-240): 8.4e-57: 203: 25.49
+	Ce
		876759 GLC7B_CAEEL (3-323): 0: 584: 89.63		Q400N3_CAEEL (49-240): 1.13e-56: 202: 25.49
+	Dm
		873549 PP11_DROME (5-323): 0: 569: 88.92		GBS76_DROME (38-269): 6.76e-53: 200: 28.51
+	Hs
		85418 PP1A_HUMAN (1-323): 0: 579: 90.66		PP13G_HUMAN (45-229): 1.58e-51: 187: 26.14
+	Hs
		967976 PP1A_HUMAN (1-323): 0: 579: 90.66		PPR3E_HUMAN (41-247): 3.95e-52: 186: 24.32
+	Ca
		1202633 Q59N42_CANAL (5-323): 0: 555: 82.50		Q5A932_CANAL (127-244): 5.29e-26: 117: 24.49