HitPredict

Interactor 1: GRIA2 (P42262)
Glutamate receptor 2 (GluR-2) (AMPA-selective glutamate receptor 2) (GluR-B) (GluR-K2) (Glutamate receptor ionotropic, AMPA 2)
Gene: GRIA2

Interactor 2: PICK1 (Q9NRD5)
PRKCA-binding protein (Protein interacting with C kinase 1) (Protein kinase C-alpha-binding protein)
Gene: PICK1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.72	0.60	0.662

Property	Details
Experiments	22232691, 11891216, 24749734
Identification Methods	pull down, two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0014069 - postsynaptic density GO:0030666 - endocytic vesicle membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 883 Hs			1 415
+	Rn
		585182 GRIA2_RAT (1-883): 0: 919: 99.55		PICK1_RAT (1-415): 0: 597: 96.39
+	Mm
		620964 GRIA2_MOUSE (1-883): 0: 921: 99.66		PICK1_MOUSE (1-415): 0: 584: 94.47
+	Rn
		585195 GRIA3_RAT (2-883): 0: 877: 71.57		PICK1_RAT (1-415): 0: 597: 96.39
+	Hs
		786764 GRIA3_HUMAN (2-883): 0: 880: 71.46		PICK1_HUMAN (1-415): 0: 592: 100.00
+	Hs
		786710 GRIA1_HUMAN (4-862): 0: 862: 70.55		PICK1_HUMAN (1-415): 0: 592: 100.00
+	Rn
		585217 GRIA4_RAT (1-860): 0: 855: 73.33		PICK1_RAT (1-415): 0: 597: 96.39
+	Hs
		816226 GRIA4_HUMAN (1-860): 0: 852: 72.40		PICK1_HUMAN (1-415): 0: 592: 100.00
+	Rn
		786686 GRIK2_RAT (3-849): 0: 788: 38.71		PICK1_RAT (1-415): 0: 597: 96.39
+	Hs
		1022367 GRIK2_HUMAN (2-849): 0: 791: 38.78		PICK1_HUMAN (1-415): 0: 592: 100.00
+	Hs
		761212 GRIK1_HUMAN (11-880): 0: 778: 36.55		PICK1_HUMAN (1-415): 0: 592: 100.00
+	Rn
		611607 GRIK1_RAT (11-853): 0: 765: 37.54		PICK1_RAT (1-415): 0: 597: 96.39