HitPredict

Interactor 1: GRIA3 (P42263)
Glutamate receptor 3 (GluR-3) (AMPA-selective glutamate receptor 3) (GluR-C) (GluR-K3) (Glutamate receptor ionotropic, AMPA 3)
Gene: GRIA3

Interactor 2: GRIP1 (Q9Y3R0)
Glutamate receptor-interacting protein 1 (GRIP-1)
Gene: GRIP1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.46	0.60	0.527

Property	Details
Experiments	11891216
Identification Methods	two hybrid, pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 894 Hs			1 1128
+	Rn
		585193 GRIA3_RAT (7-894): 0: 936: 99.44		GRIP1_RAT (1-1128): 0: 640: 93.88
+	Hs
		786750 GRIA2_HUMAN (9-894): 0: 865: 71.35		GRIP1_HUMAN (1-1128): 0: 676: 100.00
+	Hs
		786717 GRIA1_HUMAN (13-878): 0: 852: 68.20		GRIP1_HUMAN (1-1128): 0: 676: 100.00
+	Hs
		816229 GRIA4_HUMAN (13-874): 0: 851: 73.81		GRIP1_HUMAN (1-1128): 0: 676: 100.00
+	Mm
		621022 GRIA2_MOUSE (9-894): 0: 863: 71.35		GRIP1_MOUSE (1-1128): 0: 657: 95.83
+	Rn
		585169 GRIA2_RAT (9-894): 0: 862: 71.35		GRIP1_RAT (1-1128): 0: 640: 93.88
+	Rn
		585210 GRIA4_RAT (9-874): 0: 856: 74.39		GRIP1_RAT (1-1128): 0: 640: 93.88
+	Rn
		585145 GRIA1_RAT (13-878): 0: 847: 68.20		GRIP1_RAT (1-1128): 0: 640: 93.88
+	Rn
		585198 GRIA3_RAT (7-894): 0: 936: 99.44		GRIP2_RAT (1-1105): 6.49e-159: 501: 56.63
+	Rn
		585187 GRIA2_RAT (9-894): 0: 862: 71.35		GRIP2_RAT (1-1105): 6.49e-159: 501: 56.63
+	Hs
		786757 GRIA3_HUMAN (1-894): 0: 946: 100.00		DLG4_HUMAN (999-1126): 8.04e-15: 81.3: 20.74
+	Mm
		1143566 GRIA3_MOUSE (7-894): 0: 934: 98.54		DLG4_MOUSE (999-1126): 8.76e-15: 81.3: 20.74
+	Hs
		786726 GRIA2_HUMAN (9-894): 0: 865: 71.35		DLG4_HUMAN (999-1126): 8.04e-15: 81.3: 20.74
+	Mm
		620965 GRIA2_MOUSE (9-894): 0: 863: 71.35		DLG4_MOUSE (999-1126): 8.76e-15: 81.3: 20.74
+	Hs
		786696 GRIA1_HUMAN (13-878): 0: 852: 68.20		DLG1_HUMAN (9-377): 2.52e-17: 89.7: 13.17
+	Mm
		1143565 GRIA4_MOUSE (9-874): 0: 855: 73.47		DLG4_MOUSE (999-1126): 8.76e-15: 81.3: 20.74
+	Mm
		621019 GRIA2_MOUSE (9-894): 0: 863: 71.35		LNX2_MOUSE (916-1116): 1.03e-10: 67.8: 13.59
+	Rn
		585151 GRIA1_RAT (13-878): 0: 847: 68.20		DLG1_RAT (9-377): 2.47e-15: 83.2: 13.98
+	Rn
		585138 GRIA1_RAT (13-878): 0: 847: 68.20		DLG4_RAT (999-1126): 7.26e-15: 81.7: 20.74
+	Mm
		620881 GRIA1_MOUSE (13-878): 0: 844: 67.28		DLG3_MOUSE (792-1120): 2.61e-15: 83.2: 13.99