HitPredict

Interactor 1: PK3CA (P42336)
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PI3-kinase subunit alpha) (PI3K-alpha) (PI3Kalpha) (PtdIns-3-kinase subunit alpha) (EC 2.7.1.137) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha) (PtdIns-3-kinase subunit p110-alpha) (p110alpha) (Phosphoinositide 3-kinase alpha) (Phosphoinositide-3-kinase catalytic alpha polypeptide) (Serine/threonine protein kinase PIK3CA) (EC 2.7.11.1)
Gene: PIK3CA

Interactor 2: MYH14 (Q7Z406)
Myosin-14 (Myosin heavy chain 14) (Myosin heavy chain, non-muscle IIc) (Non-muscle myosin heavy chain IIc) (NMHC II-C)
Gene: MYH14

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	34591642
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 1068 Hs			1 1995
+	Hs
		724697 PK3CA_HUMAN (1-1068): 0: 1325: 100.00		MYH9_HUMAN (1010-1995): 3.22e-56: 219: 16.62
+	Hs
		725105 PK3CA_HUMAN (1-1068): 0: 1325: 100.00		MYH10_HUMAN (1656-1994): 1.36e-12: 75.9: 12.39
+	Hs
		128818 P3C2A_HUMAN (300-1064): 0: 727: 31.92		MYH9_HUMAN (1010-1995): 3.22e-56: 219: 16.62
+	Hs
		724921 PK3C3_HUMAN (348-646): 4.24e-71: 257: 23.01		MYH9_HUMAN (1010-1995): 3.22e-56: 219: 16.62
+	Hs
		522561 PK3C3_HUMAN (348-646): 4.24e-71: 257: 23.01		MYH1_HUMAN (1150-1995): 2.05e-53: 209: 15.50