HitPredict

Interactor 1: PK3CA (P42336)
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PI3-kinase subunit alpha) (PI3K-alpha) (PI3Kalpha) (PtdIns-3-kinase subunit alpha) (EC 2.7.1.137) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha) (PtdIns-3-kinase subunit p110-alpha) (p110alpha) (Phosphoinositide 3-kinase alpha) (Phosphoinositide-3-kinase catalytic alpha polypeptide) (Serine/threonine protein kinase PIK3CA) (EC 2.7.11.1)
Gene: PIK3CA

Interactor 2: MYO19 (Q96H55)
Unconventional myosin-XIX (Myosin head domain-containing protein 1)
Gene: MYO19

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	34591642
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1068 Hs			1 970
+	Hs
		787337 PK3CA_HUMAN (1-1068): 0: 1325: 100.00		MYO5A_HUMAN (10-937): 0: 1027: 29.21
+	Hs
		725105 PK3CA_HUMAN (1-1068): 0: 1325: 100.00		MYH10_HUMAN (2-965): 0: 998: 26.14
+	Hs
		724697 PK3CA_HUMAN (1-1068): 0: 1325: 100.00		MYH9_HUMAN (9-907): 0: 997: 28.63
+	Hs
		128898 P3C2A_HUMAN (300-1064): 0: 727: 31.92		MYO19_HUMAN (1-970): 0: 1069: 100.00
+	Hs
		128818 P3C2A_HUMAN (300-1064): 0: 727: 31.92		MYH9_HUMAN (9-907): 0: 997: 28.63
+	Hs
		787329 PK3CA_HUMAN (1-1068): 0: 1325: 100.00		MYO6_HUMAN (50-677): 1.69e-119: 397: 36.01
+	Hs
		128920 P3C2A_HUMAN (300-1064): 0: 727: 31.92		MYO10_HUMAN (1-945): 0: 991: 26.68
+	Hs
		724921 PK3C3_HUMAN (348-646): 4.24e-71: 257: 23.01		MYH9_HUMAN (9-907): 0: 997: 28.63
+	Hs
		522561 PK3C3_HUMAN (348-646): 4.24e-71: 257: 23.01		MYH1_HUMAN (12-802): 0: 980: 30.54
+	Hs
		128931 P3C2A_HUMAN (300-1064): 0: 727: 31.92		MYO6_HUMAN (50-677): 1.69e-119: 397: 36.01