Interactor 1: MTOR (P42345)
Serine/threonine-protein kinase mTOR (EC 2.7.11.1) (FK506-binding protein 12-rapamycin complex-associated protein 1) (FKBP12-rapamycin complex-associated protein) (Mammalian target of rapamycin) (mTOR) (Mechanistic target of rapamycin) (Rapamycin and FKBP12 target 1) (Rapamycin target protein 1)
Gene: MTOR

Interactor 2: LTOR2 (Q9Y2Q5)
Ragulator complex protein LAMTOR2 (Endosomal adaptor protein p14) (Late endosomal/lysosomal Mp1-interacting protein) (Late endosomal/lysosomal adaptor and MAPK and MTOR activator 2) (Mitogen-activated protein-binding protein-interacting protein) (MAPBP-interacting protein) (Roadblock domain-containing protein 3)
Gene: LAMTOR2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.54 0.55 0.547

The method score is based on:

Property Details
Experiments 20381137, 22980980
Identification Methods affinity chromatography technology, cross-linking study
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001558 - regulation of cell growth
GO:0005765 - lysosomal membrane
GO:0038202 - TORC1 signaling
GO:0071230 - cellular response to amino acid stimulus
Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024