HitPredict

Interactor 1: EPS15 (P42566)
Epidermal growth factor receptor substrate 15 (Protein Eps15) (Protein AF-1p)
Gene: EPS15

Interactor 2: SGIP1 (Q9BQI5)
SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin-3-interacting protein)
Gene: SGIP1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.75 0.60 0.674

The method score is based on:

Property Details
Experiments 26822536, 27237791, 33961781
Identification Methods pull down, x-ray crystallography, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type direct interaction, association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0005905 - clathrin-coated pit
GO:0017124 - SH3 domain binding
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 896
Hs

1 828
+ Mm
+ Hs
+ Hs
+ Hs
+ Rn
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024