HitPredict

Interactor 1: AF9 (P42568)
Protein AF-9 (ALL1-fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3)
Gene: MLLT3

Interactor 2: AF17 (P55198)
Protein AF-17 (ALL1-fused gene from chromosome 17 protein)
Gene: MLLT6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.675

Property	Details
Experiments	28514442, 33961781, 20203130
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0042393 - histone binding
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 568 Hs			1 1093
+	Hs
		788017 AF9_HUMAN (1-568): 1.02e-96: 307: 100.00		AF10_HUMAN (1-1026): 6.33e-95: 328: 37.14
+	Hs
		876592 ENL_HUMAN (1-567): 1.44e-70: 238: 50.00		AF17_HUMAN (1-1093): 1.44e-115: 385: 100.00
+	Hs
		876561 ENL_HUMAN (1-567): 1.44e-70: 238: 50.00		AF10_HUMAN (1-1026): 6.33e-95: 328: 37.14
+	Hs
		317422 YETS4_HUMAN (6-190): 1.98e-45: 161: 20.42		AF17_HUMAN (1-1093): 1.44e-115: 385: 100.00
+	Hs
		317421 YETS4_HUMAN (6-190): 1.98e-45: 161: 20.42		AF10_HUMAN (1-1026): 6.33e-95: 328: 37.14
+	Hs
		1356824 YETS2_HUMAN (3-516): 6.41e-51: 191: 14.68		BRPF3_HUMAN (3-278): 7.78e-69: 254: 31.82
+	Sc
		715757 TAF14_YEAST (6-186): 2.13e-31: 124: 20.97		NTO1_YEAST (4-260): 5.49e-84: 290: 31.40