HitPredict

Interactor 1: AF9 (P42568)
Protein AF-9 (ALL1-fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3)
Gene: MLLT3

Interactor 2: PCGF1 (Q9BSM1)
Polycomb group RING finger protein 1 (Nervous system Polycomb-1) (NSPc1) (RING finger protein 68)
Gene: PCGF1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	27505670, 20431927
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 568 Hs			1 259
+	Hs
		974513 ENL_HUMAN (1-567): 1.44e-70: 238: 50.00		PCGF1_HUMAN (1-259): 4.13e-82: 248: 100.00
+	Hs
		788060 AF9_HUMAN (1-568): 1.02e-96: 307: 100.00		RING2_HUMAN (24-259): 7.12e-39: 140: 16.88
+	Mm
		57329 AF9_MOUSE (1-568): 3.37e-95: 303: 98.24		RING2_MOUSE (24-259): 5.08e-39: 140: 16.88
+	Hs
		717730 ENL_HUMAN (1-567): 1.44e-70: 238: 50.00		BMI1_HUMAN (30-255): 1.92e-63: 203: 35.29
+	Hs
		974511 ENL_HUMAN (1-567): 1.44e-70: 238: 50.00		RING2_HUMAN (24-259): 7.12e-39: 140: 16.88
+	Mm
		1208638 Q8CJ76_MOUSE (1-567): 2.17e-69: 235: 49.56		RING2_MOUSE (24-259): 5.08e-39: 140: 16.88
+	Mm
		1321740 Q9ERL0_MOUSE (1-567): 6.16e-69: 233: 48.86		RING2_MOUSE (24-259): 5.08e-39: 140: 16.88
+	Hs
		718055 TITIN_HUMAN (145-514): 7.97e-09: 61.2: 10.86		BMI1_HUMAN (30-255): 1.92e-63: 203: 35.29
+	Hs
		282445 YETS4_HUMAN (6-190): 1.98e-45: 161: 20.42		RNF8_HUMAN (24-130): 3e-10: 61.7: 28.04
+	Hs
		1246355 THOC2_HUMAN (144-455): 1.47e-10: 66.6: 10.13		RING2_HUMAN (24-259): 7.12e-39: 140: 16.88
+	Hs
		1264788 TITIN_HUMAN (145-514): 7.97e-09: 61.2: 10.86		RING2_HUMAN (24-259): 7.12e-39: 140: 16.88