HitPredict

Interactor 1: CASP3 (P42574)
Caspase-3 (CASP-3) (EC 3.4.22.56) (Apopain) (Cysteine protease CPP32) (CPP-32) (Protein Yama) (SREBP cleavage activity 1) (SCA-1) [Cleaved into: Caspase-3 subunit p17; Caspase-3 subunit p12]
Gene: CASP3

Interactor 2: BIRC6 (Q9NR09)
Baculoviral IAP repeat-containing protein 6 (EC 2.3.2.27) (BIR repeat-containing ubiquitin-conjugating enzyme) (BRUCE) (RING-type E3 ubiquitin transferase BIRC6) (Ubiquitin-conjugating BIR domain enzyme apollon) (APOLLON)
Gene: BIRC6

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.82 1.00 0.909

The method score is based on:

Property Details
Experiments 36758106, 36758104, 15200957, 15507451
Identification Methods enzymatic study, pull down, fluorescent resonance energy transfer, x-ray crystallography, affinity chromatography technology
Interaction Type direct interaction, association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains BIR~Peptidase_C14
Common GO terms GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0006915 - apoptotic process
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

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Hs

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Last updated: 15 Jul 2024