Interactor 1: NKX25 (P42582)
Homeobox protein Nkx-2.5 (Cardiac-specific homeobox) (Homeobox protein CSX) (Homeobox protein NK-2 homolog E)
Gene: Nkx2-5

Interactor 2: HAND2 (Q61039)
Heart- and neural crest derivatives-expressed protein 2 (Deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2) (dHAND) (Helix-loop-helix transcription factor expressed in embryo and deciduum) (Thing-2)
Gene: HAND2

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 12392994
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001947 - heart looping
GO:0003007 - heart morphogenesis
GO:0003151 - outflow tract morphogenesis
and 20 others

more...

Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 318
Mm

1 217
+ Mm
+ Hs
+ Hs
+ Hs
+ Dm
+ Dm
+ Hs
+ Dm
+ Dm
+ Dm
+ Hs

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Last updated: 15 Jul 2024