HitPredict

Interactor 1: TEC (P42680)
Tyrosine-protein kinase Tec (EC 2.7.10.2)
Gene: TEC

Interactor 2: ADA15 (Q13444)
Disintegrin and metalloproteinase domain-containing protein 15 (ADAM 15) (EC 3.4.24.-) (Metalloprotease RGD disintegrin protein) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 15) (MDC-15) (Metargidin)
Gene: ADAM15

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	25825872
Identification Methods	phage display
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0007229 - integrin-mediated signaling pathway GO:0042246 - tissue regeneration GO:0046872 - metal ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 631 Hs			1 863
+	Hs
		788989 TEC_HUMAN (1-631): 0: 738: 100.00		ADAM9_HUMAN (31-823): 4.3e-168: 510: 31.00
+	Hs
		996560 ITK_HUMAN (1-625): 0: 691: 57.58		ADA15_HUMAN (1-863): 0: 556: 100.00
+	Hs
		789007 TEC_HUMAN (1-631): 0: 738: 100.00		ADA19_HUMAN (8-859): 3.95e-164: 504: 33.00
+	Hs
		788983 TEC_HUMAN (1-631): 0: 738: 100.00		ADAM8_HUMAN (1-851): 5.57e-160: 489: 31.26
+	Hs
		986371 BTK_HUMAN (5-627): 0: 629: 52.50		ADA15_HUMAN (1-863): 0: 556: 100.00
+	Hs
		337463 ABL1_HUMAN (143-624): 2.71e-169: 514: 37.30		ADA15_HUMAN (1-863): 0: 556: 100.00
+	Hs
		522964 SRC_HUMAN (127-627): 2.29e-166: 487: 35.24		ADA15_HUMAN (1-863): 0: 556: 100.00
+	Hs
		433344 YES_HUMAN (111-627): 3.51e-163: 479: 34.08		ADA15_HUMAN (1-863): 0: 556: 100.00
+	Hs
		442824 HCK_HUMAN (98-628): 1.96e-161: 474: 34.02		ADA15_HUMAN (1-863): 0: 556: 100.00
+	Hs
		152277 ITK_HUMAN (1-625): 0: 691: 57.58		ADA10_HUMAN (69-525): 5.98e-94: 313: 23.44
+	Hs
		197583 SRC_HUMAN (127-627): 2.29e-166: 487: 35.24		ADA12_HUMAN (42-856): 8.46e-167: 509: 35.32
+	Hs
		523142 SRC_HUMAN (127-627): 2.29e-166: 487: 35.24		ADA19_HUMAN (8-859): 3.95e-164: 504: 33.00
+	Hs
		197581 HCK_HUMAN (98-628): 1.96e-161: 474: 34.02		ADA12_HUMAN (42-856): 8.46e-167: 509: 35.32
+	Hs
		442882 HCK_HUMAN (98-628): 1.96e-161: 474: 34.02		ADA19_HUMAN (8-859): 3.95e-164: 504: 33.00
+	Hs
		522899 SRC_HUMAN (127-627): 2.29e-166: 487: 35.24		ADAM8_HUMAN (1-851): 5.57e-160: 489: 31.26
+	Hs
		152218 ABL1_HUMAN (143-624): 2.71e-169: 514: 37.30		ADA10_HUMAN (69-525): 5.98e-94: 313: 23.44
+	Hs
		152242 SRC_HUMAN (127-627): 2.29e-166: 487: 35.24		ADA10_HUMAN (69-525): 5.98e-94: 313: 23.44
+	Hs
		152229 YES_HUMAN (111-627): 3.51e-163: 479: 34.08		ADA10_HUMAN (69-525): 5.98e-94: 313: 23.44
+	Hs
		152233 HCK_HUMAN (98-628): 1.96e-161: 474: 34.02		ADA10_HUMAN (69-525): 5.98e-94: 313: 23.44
+	Hs
		522906 SRC_HUMAN (127-627): 2.29e-166: 487: 35.24		ADA17_HUMAN (348-534): 2.91e-20: 98.6: 32.29