HitPredict

Interactor 1: ABL2 (P42684)
Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Abelson tyrosine-protein kinase 2) (Abelson-related gene protein) (Tyrosine-protein kinase ARG)
Gene: ABL2

Interactor 2: M3K10 (Q02779)
Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST)
Gene: MAP3K10

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.48 1.00 0.698

The method score is based on:

Property Details
Experiments 20936779
Identification Methods two hybrid, two hybrid pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PK_Tyr_Ser-Thr~PK_Tyr_Ser-Thr, PK_Tyr_Ser-Thr~SH3_9, PK_Tyr_Ser-Thr~SH2, PK_Tyr_Ser-Thr~SH3_1
Common GO terms GO:0004672 - protein kinase activity
GO:0005524 - ATP binding
GO:0007165 - signal transduction
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 1182
Hs

1 954
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024