HitPredict

Interactor 1: FRK (P42685)
Tyrosine-protein kinase FRK (EC 2.7.10.2) (FYN-related kinase) (Nuclear tyrosine protein kinase RAK) (Protein-tyrosine kinase 5)
Gene: FRK

Interactor 2: PHAG1 (Q9NWQ8)
Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 (Csk-binding protein) (Transmembrane adapter protein PAG) (Transmembrane phosphoprotein Cbp)
Gene: PAG1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	36736316
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PAG~SH2
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 505 Hs			1 432
+	Mm
		763390 FYN_MOUSE (30-503): 2.04e-177: 510: 50.63		PHAG1_MOUSE (1-432): 0: 759: 78.21
+	Hs
		523175 SRC_HUMAN (13-503): 1.23e-178: 513: 47.89		PHAG1_HUMAN (1-432): 0: 755: 100.00
+	Hs
		412375 FYN_HUMAN (30-503): 1.55e-177: 511: 50.63		PHAG1_HUMAN (1-432): 0: 755: 100.00
+	Mm
		411925 LCK_MOUSE (33-495): 8.53e-173: 498: 48.29		PHAG1_MOUSE (1-432): 0: 759: 78.21
+	Hs
		411873 LCK_HUMAN (33-495): 2.21e-173: 499: 48.50		PHAG1_HUMAN (1-432): 0: 755: 100.00
+	Mm
		976830 ITK_MOUSE (5-493): 8.3e-170: 494: 33.00		PHAG1_MOUSE (1-432): 0: 759: 78.21
+	Mm
		782848 CSK_MOUSE (48-494): 1.66e-167: 482: 37.00		PHAG1_MOUSE (1-432): 0: 759: 78.21
+	Hs
		337571 ABL1_HUMAN (33-495): 1.24e-159: 484: 42.03		PHAG1_HUMAN (1-432): 0: 755: 100.00
+	Mm
		639443 LYN_MOUSE (21-495): 6.24e-165: 478: 49.48		PHAG1_MOUSE (1-432): 0: 759: 78.21
+	Hs
		434038 LYN_HUMAN (21-495): 3.53e-166: 481: 49.27		PHAG1_HUMAN (1-432): 0: 755: 100.00
+	Hs
		782829 CSK_HUMAN (48-494): 6.43e-167: 480: 36.78		PHAG1_HUMAN (1-432): 0: 755: 100.00
+	Rn
		693647 CSK_RAT (48-494): 2.19e-167: 482: 37.00		PHAG1_RAT (1-432): 0: 740: 79.13