HitPredict

Interactor 1: LIFR (P42702)
Leukemia inhibitory factor receptor (LIF receptor) (LIF-R) (CD antigen CD118)
Gene: LIFR

Interactor 2: FBX6 (Q9NRD1)
F-box only protein 6 (F-box protein that recognizes sugar chains 2) (F-box/G-domain protein 2)
Gene: FBXO6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	22268729
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1097 Hs			1 293
+	Hs
		789685 LIFR_HUMAN (1-1097): 0: 676: 100.00		FBX2_HUMAN (23-259): 3.78e-119: 345: 49.17
+	Hs
		817333 LEPR_HUMAN (231-720): 2.28e-132: 433: 20.53		FBX6_HUMAN (1-293): 1.15e-178: 495: 100.00
+	Hs
		817334 LEPR_HUMAN (231-720): 2.28e-132: 433: 20.53		FBX2_HUMAN (23-259): 3.78e-119: 345: 49.17
+	Hs
		1032034 PTPRS_HUMAN (458-1092): 2.48e-45: 181: 12.02		FBX6_HUMAN (1-293): 1.15e-178: 495: 100.00
+	Hs
		685320 L1CAM_HUMAN (318-1059): 1.18e-27: 123: 10.45		FBX6_HUMAN (1-293): 1.15e-178: 495: 100.00
+	Hs
		1018314 CNTN1_HUMAN (144-1093): 3.19e-70: 256: 9.44		FBX2_HUMAN (23-259): 3.78e-119: 345: 49.17
+	Hs
		1032042 PTPRS_HUMAN (458-1092): 2.48e-45: 181: 12.02		FBX2_HUMAN (23-259): 3.78e-119: 345: 49.17
+	Hs
		1356264 ROBO1_HUMAN (2-527): 1.55e-34: 146: 11.36		FBX2_HUMAN (23-259): 3.78e-119: 345: 49.17
+	Hs
		685328 L1CAM_HUMAN (318-1059): 1.18e-27: 123: 10.45		FBX2_HUMAN (23-259): 3.78e-119: 345: 49.17
+	Hs
		770211 IL6RB_HUMAN (42-531): 3.09e-13: 76.6: 15.58		FBX2_HUMAN (23-259): 3.78e-119: 345: 49.17
+	Hs
		1305437 OSMR_HUMAN (50-542): 4.28e-12: 72.8: 11.87		FBX2_HUMAN (23-259): 3.78e-119: 345: 49.17
+	Hs
		1123262 SDK2_HUMAN (326-636): 8.07e-11: 68.7: 18.32		FBX2_HUMAN (23-259): 3.78e-119: 345: 49.17