HitPredict

Interactor 1: UBC2 (P42745)
Ubiquitin-conjugating enzyme E2 2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme 2) (Ubiquitin carrier protein 2) (Ubiquitin-conjugating enzyme E2-17 kDa 2) (Ubiquitin-protein ligase 2)
Gene: UBC2

Interactor 2: BRE1B (Q9C895)
E3 ubiquitin-protein ligase BRE1-like 2 (EC 2.3.2.27) (Protein HISTONE MONOUBIQUITINATION 2) (AtHUB2) (RING-type E3 ubiquitin transferase BRE1-like 2)
Gene: HUB2

Species: Arabidopsis thaliana

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.34	1.00	0.590

Property	Details
Experiments	18849490
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	UQ_con~zf-C3HC4_3
Common GO terms	GO:0010228 - vegetative to reproductive phase transition of meristem
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 152 At			1 900
+	At
		639387 UBC1_ARATH (1-152): 6.06e-75: 221: 98.68		BRE1B_ARATH (1-900): 2.37e-68: 246: 100.00
+	Hs
		919748 UB2D2_HUMAN (5-150): 1.76e-79: 233: 45.89		BRE1A_HUMAN (46-900): 8.27e-47: 183: 19.03
+	At
		790156 UBC2_ARATH (1-152): 4.51e-75: 222: 100.00		BRE1A_ARATH (55-900): 6.84e-48: 186: 28.77
+	At
		639386 UBC1_ARATH (1-152): 6.06e-75: 221: 98.68		BRE1A_ARATH (55-900): 6.84e-48: 186: 28.77
+	Ce
		712245 UBC2_CAEEL (5-150): 2.14e-79: 233: 44.52		BRE1_CAEEL (45-900): 1.29e-43: 172: 15.73
+	Hs
		829017 UBE2A_HUMAN (1-149): 5.99e-74: 219: 76.51		BRE1A_HUMAN (46-900): 8.27e-47: 183: 19.03
+	Hs
		851821 UB2E1_HUMAN (3-150): 1.49e-72: 217: 36.49		BRE1A_HUMAN (46-900): 8.27e-47: 183: 19.03
+	Hs
		927757 UBE2B_HUMAN (1-149): 2.9e-73: 217: 75.84		BRE1A_HUMAN (46-900): 8.27e-47: 183: 19.03
+	Ce
		712246 UBC1_CAEEL (1-149): 9.19e-73: 218: 72.48		BRE1_CAEEL (45-900): 1.29e-43: 172: 15.73
+	Sc
		410240 UBC2_YEAST (1-150): 2.4e-76: 226: 64.67		BRE1_YEAST (346-900): 8.27e-25: 112: 16.09
+	Hs
		256237 UB2D2_HUMAN (5-150): 1.76e-79: 233: 45.89		BRE1B_HUMAN (4-713): 1.1e-11: 70.9: 8.89
+	Sp
		618356 UBC2_SCHPO (1-151): 5.35e-71: 211: 70.86		BRL1_SCHPO (239-895): 1.75e-18: 92.6: 14.35
+	Sp
		251716 UBC2_SCHPO (1-151): 5.35e-71: 211: 70.86		BRL2_SCHPO (457-895): 3.95e-18: 91.5: 16.95
+	Hs
		256227 UBE2A_HUMAN (1-149): 5.99e-74: 219: 76.51		BRE1B_HUMAN (4-713): 1.1e-11: 70.9: 8.89
+	Hs
		256229 UB2E1_HUMAN (3-150): 1.49e-72: 217: 36.49		BRE1B_HUMAN (4-713): 1.1e-11: 70.9: 8.89
+	Hs
		256239 UBE2B_HUMAN (1-149): 2.9e-73: 217: 75.84		BRE1B_HUMAN (4-713): 1.1e-11: 70.9: 8.89