Interactor 1: WASP (P42768)
Actin nucleation-promoting factor WAS (Wiskott-Aldrich syndrome protein) (WASp)
Gene: WAS

Interactor 2: WASP (P42768)
Actin nucleation-promoting factor WAS (Wiskott-Aldrich syndrome protein) (WASp)
Gene: WAS

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.71 1.00 0.847

The method score is based on:

Property Details
Experiments 18650809, 10724160, 12769847
Identification Methods pull down, classical fluorescence spectroscopy
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PBD~PBD, WH1~WH1, WH2~WH2
Common GO terms GO:0002625 - regulation of T cell antigen processing and presentation
GO:0003779 - actin binding
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0005884 - actin filament
and 31 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 502
Hs

1 502
+ Rn
+ Bt
+ Hs
+ Hs
+ Sc
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Sc
+ Hs
+ Rn

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024