Interactor 1: WASP (P42768)
Actin nucleation-promoting factor WAS (Wiskott-Aldrich syndrome protein) (WASp)
Gene: WAS
Interactor 2: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.97 | 1.00 | 0.986 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 10713100, 20936779, 10360579, 10684602, 28539360, 10724160, 8643625, 8625410, 15075243, 10360578, 25502805, 31515488, 9422512, 22252508, 9660763, 15361624 |
| Identification Methods | pull down, two hybrid, affinity chromatography technology, nuclear magnetic resonance, two hybrid array, two hybrid pooling approach, far western blotting, classical fluorescence spectroscopy, surface plasmon resonance, circular dichroism and 1 others
more... |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PBD~Ras |
| Common GO terms | GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0005911 - cell-cell junction GO:0010591 - regulation of lamellipodium assembly GO:0019901 - protein kinase binding and 5 others more... |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
