Interactor 1: WASP (P42768)
Actin nucleation-promoting factor WAS (Wiskott-Aldrich syndrome protein) (WASp)
Gene: WAS

Interactor 2: ARP2 (P61160)
Actin-related protein 2 (Actin-like protein 2)
Gene: ACTR2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 1.00 0.827

The method score is based on:

Property Details
Experiments 35768435, 24872192, 12769847
Identification Methods pull down, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Actin~WH2
Common GO terms GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0015629 - actin cytoskeleton
GO:0035861 - site of double-strand break
GO:0045944 - positive regulation of transcription by RNA polymerase II
and 3 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 502
Hs

1 394
+ Hs
+ Bt
+ Hs
+ Hs
+ Hs
+ Ce
+ Hs
+ Hs
+ Sp
+ Sc
+ Sp
+ Hs
+ Sc
+ Hs

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Last updated: 15 Jul 2024