HitPredict

Interactor 1: WASP (P42768)
Actin nucleation-promoting factor WAS (Wiskott-Aldrich syndrome protein) (WASp)
Gene: WAS

Interactor 2: BTK (Q06187)
Tyrosine-protein kinase BTK (EC 2.7.10.2) (Agammaglobulinemia tyrosine kinase) (ATK) (B-cell progenitor kinase) (BPK) (Bruton tyrosine kinase)
Gene: BTK

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.80 0.60 0.696

The method score is based on:

Property Details
Experiments 8892607, 10427990, 10068673, 9742969
Identification Methods pull down, affinity chromatography technology, anti tag coimmunoprecipitation, protein kinase assay
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0043274 - phospholipase binding
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 502
Hs

1 659
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024