HitPredict

Interactor 1: CDN2A (P42771)
Cyclin-dependent kinase inhibitor 2A (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (Multiple tumor suppressor 1) (MTS-1) (p16-INK4a) (p16-INK4) (p16INK4A)
Gene: CDKN2A

Interactor 2: CDN2B (P42772)
Cyclin-dependent kinase 4 inhibitor B (Multiple tumor suppressor 2) (MTS-2) (p14-INK4b) (p15-INK4b) (p15INK4B)
Gene: CDKN2B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.58 0.60 0.595

The method score is based on:

Property Details
Experiments 28205554, 24981860
Identification Methods fluorescent resonance energy transfer, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0004861 - cyclin-dependent protein serine/threonine kinase inhibitor activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0007049 - cell cycle
and 5 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 156
Hs

1 138
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024