HitPredict

Interactor 1: CDN2A (P42771)
Cyclin-dependent kinase inhibitor 2A (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (Multiple tumor suppressor 1) (MTS-1) (p16-INK4a) (p16-INK4) (p16INK4A)
Gene: CDKN2A

Interactor 2: RND2 (P52198)
Rho-related GTP-binding protein RhoN (Rho family GTPase 2) (Rho-related GTP-binding protein Rho7) (Rnd2)
Gene: RND2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0019901 - protein kinase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 156 Hs			1 227
+	Hs
		852678 ANR26_HUMAN (2-155): 9.25e-33: 123: 18.59		RND2_HUMAN (1-227): 7.71e-110: 316: 100.00
+	Hs
		901141 ANK3_HUMAN (15-155): 1.26e-35: 132: 21.13		RND3_HUMAN (4-227): 3.64e-100: 292: 64.00
+	Hs
		790732 CDN2A_HUMAN (1-156): 1.38e-51: 163: 100.00		RHOA_HUMAN (9-193): 2.25e-83: 248: 47.03
+	Hs
		790729 CDN2A_HUMAN (1-156): 1.38e-51: 163: 100.00		RAC3_HUMAN (8-182): 2.88e-76: 230: 42.86
+	Hs
		545247 CDN2A_HUMAN (1-156): 1.38e-51: 163: 100.00		RAC2_HUMAN (8-195): 4.31e-76: 229: 40.43
+	Hs
		790746 CDN2A_HUMAN (1-156): 1.38e-51: 163: 100.00		RHOG_HUMAN (7-193): 2.82e-75: 227: 41.71
+	Hs
		900423 ANK3_HUMAN (15-155): 1.26e-35: 132: 21.13		RHOA_HUMAN (9-193): 2.25e-83: 248: 47.03
+	Hs
		925204 ANK2_HUMAN (3-155): 1.76e-37: 137: 17.37		RAC1_HUMAN (8-194): 1.25e-78: 235: 42.25
+	Hs
		901057 ANR26_HUMAN (2-155): 9.25e-33: 123: 18.59		RHOA_HUMAN (9-193): 2.25e-83: 248: 47.03
+	Hs
		925238 ANK3_HUMAN (15-155): 1.26e-35: 132: 21.13		RAC1_HUMAN (8-194): 1.25e-78: 235: 42.25
+	Hs
		436576 ANR26_HUMAN (2-155): 9.25e-33: 123: 18.59		RHOC_HUMAN (9-193): 3.15e-81: 242: 48.11
+	Hs
		950953 ANK3_HUMAN (15-155): 1.26e-35: 132: 21.13		RHOG_HUMAN (7-193): 2.82e-75: 227: 41.71
+	Hs
		892683 ANR26_HUMAN (2-155): 9.25e-33: 123: 18.59		RAC3_HUMAN (8-182): 2.88e-76: 230: 42.86
+	Hs
		790737 CDN2A_HUMAN (1-156): 1.38e-51: 163: 100.00		RHOB_HUMAN (7-184): 9.27e-58: 182: 46.63
+	Hs
		120334 CDN2A_HUMAN (1-156): 1.38e-51: 163: 100.00		RHOD_HUMAN (9-191): 9.02e-55: 176: 43.48
+	Hs
		790884 CDN2A_HUMAN (1-156): 1.38e-51: 163: 100.00		RHOF_HUMAN (9-191): 9.16e-51: 165: 43.01
+	Hs
		915638 ANK3_HUMAN (15-155): 1.26e-35: 132: 21.13		RHOB_HUMAN (7-184): 9.27e-58: 182: 46.63
+	Hs
		120412 ANK3_HUMAN (15-155): 1.26e-35: 132: 21.13		RHOD_HUMAN (9-191): 9.02e-55: 176: 43.48
+	Hs
		120716 ANR26_HUMAN (2-155): 9.25e-33: 123: 18.59		RHOD_HUMAN (9-191): 9.02e-55: 176: 43.48
+	Hs
		1021465 ANK3_HUMAN (15-155): 1.26e-35: 132: 21.13		RHOF_HUMAN (9-191): 9.16e-51: 165: 43.01