HitPredict

Interactor 1: CDN2A (P42771)
Cyclin-dependent kinase inhibitor 2A (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (Multiple tumor suppressor 1) (MTS-1) (p16-INK4a) (p16-INK4) (p16INK4A)
Gene: CDKN2A

Interactor 2: TBB4B (P68371)
Tubulin beta-4B chain (Tubulin beta-2 chain) (Tubulin beta-2C chain)
Gene: TUBB4B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.516

Property	Details
Experiments	17955473
Identification Methods	pull down
Interaction Type	direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 156 Hs			1 445
+	Hs
		428073 CDN2A_HUMAN (1-156): 1.38e-51: 163: 100.00		TBB5_HUMAN (1-429): 0: 711: 98.37
+	Hs
		428145 ANK2_HUMAN (3-155): 1.76e-37: 137: 17.37		TBB5_HUMAN (1-429): 0: 711: 98.37
+	Hs
		965103 ANK2_HUMAN (3-155): 1.76e-37: 137: 17.37		TBB2A_HUMAN (1-430): 0: 707: 97.67
+	Hs
		883508 RIPK4_HUMAN (9-155): 1.21e-30: 117: 25.68		TBB3_HUMAN (1-443): 0: 714: 93.23
+	Hs
		1037393 Q9H4D1_HUMAN (9-155): 2.04e-30: 116: 25.68		TBB3_HUMAN (1-443): 0: 714: 93.23
+	Hs
		60334 POTEF_HUMAN (1-130): 1.26e-29: 115: 19.55		TBB3_HUMAN (1-443): 0: 714: 93.23
+	Hs
		428113 RIPK4_HUMAN (9-155): 1.21e-30: 117: 25.68		TBB5_HUMAN (1-429): 0: 711: 98.37
+	Hs
		883476 RIPK4_HUMAN (9-155): 1.21e-30: 117: 25.68		TBB4B_HUMAN (1-427): 0: 711: 100.00
+	Hs
		428431 Q9H4D1_HUMAN (9-155): 2.04e-30: 116: 25.68		TBB5_HUMAN (1-429): 0: 711: 98.37
+	Hs
		883632 RIPK4_HUMAN (9-155): 1.21e-30: 117: 25.68		TBB2B_HUMAN (1-430): 0: 710: 98.14
+	Hs
		933974 Q9H4D1_HUMAN (9-155): 2.04e-30: 116: 25.68		TBB4B_HUMAN (1-427): 0: 711: 100.00
+	Hs
		1313672 Q9H4D1_HUMAN (9-155): 2.04e-30: 116: 25.68		TBB2B_HUMAN (1-430): 0: 710: 98.14
+	Hs
		60278 POTEF_HUMAN (1-130): 1.26e-29: 115: 19.55		TBB5_HUMAN (1-429): 0: 711: 98.37
+	Hs
		60319 POTEF_HUMAN (1-130): 1.26e-29: 115: 19.55		TBB4B_HUMAN (1-427): 0: 711: 100.00
+	Hs
		883510 RIPK4_HUMAN (9-155): 1.21e-30: 117: 25.68		TBB2A_HUMAN (1-430): 0: 707: 97.67
+	Hs
		1046578 Q9H4D1_HUMAN (9-155): 2.04e-30: 116: 25.68		TBB2A_HUMAN (1-430): 0: 707: 97.67
+	Hs
		381154 RIPK4_HUMAN (9-155): 1.21e-30: 117: 25.68		TBB4A_HUMAN (1-427): 0: 706: 98.60
+	Hs
		883630 RIPK4_HUMAN (9-155): 1.21e-30: 117: 25.68		TBB6_HUMAN (1-432): 0: 706: 92.36
+	Hs
		1312810 Q9H4D1_HUMAN (9-155): 2.04e-30: 116: 25.68		TBB6_HUMAN (1-432): 0: 706: 92.36
+	Hs
		381300 Q9H4D1_HUMAN (9-155): 2.04e-30: 116: 25.68		TBB4A_HUMAN (1-427): 0: 706: 98.60