HitPredict

Interactor 1: CDN2A (P42771)
Cyclin-dependent kinase inhibitor 2A (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (Multiple tumor suppressor 1) (MTS-1) (p16-INK4a) (p16-INK4) (p16INK4A)
Gene: CDKN2A

Interactor 2: CUL2 (Q13617)
Cullin-2 (CUL-2)
Gene: CUL2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	33504946, 35468939, 21145461
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 156 Hs			1 745
+	Hs
		790769 CDN2A_HUMAN (1-156): 1.38e-51: 163: 100.00		CUL1_HUMAN (6-745): 0: 775: 36.24
+	Hs
		790771 CDN2A_HUMAN (1-156): 1.38e-51: 163: 100.00		CUL3_HUMAN (1-745): 0: 768: 26.38
+	Hs
		1021398 ANK3_HUMAN (15-155): 1.26e-35: 132: 21.13		CUL4A_HUMAN (4-745): 0: 773: 26.86
+	Hs
		1021397 ANK3_HUMAN (15-155): 1.26e-35: 132: 21.13		CUL3_HUMAN (1-745): 0: 768: 26.38
+	Hs
		556700 ANK1_HUMAN (2-130): 2.4e-33: 125: 24.62		CUL3_HUMAN (1-745): 0: 768: 26.38
+	Hs
		883509 RIPK4_HUMAN (9-155): 1.21e-30: 117: 25.68		CUL1_HUMAN (6-745): 0: 775: 36.24
+	Hs
		1041199 Q9H4D1_HUMAN (9-155): 2.04e-30: 116: 25.68		CUL1_HUMAN (6-745): 0: 775: 36.24
+	Hs
		1042562 EHMT1_HUMAN (4-121): 1.19e-30: 117: 19.33		CUL3_HUMAN (1-745): 0: 768: 26.38
+	Hs
		1042298 EHMT2_HUMAN (4-114): 3.84e-29: 113: 24.11		CUL3_HUMAN (1-745): 0: 768: 26.38
+	Hs
		1043588 ASB8_HUMAN (60-153): 1.29e-19: 84.2: 21.28		CUL4B_HUMAN (4-745): 0: 771: 27.79
+	Hs
		1042317 ANR27_HUMAN (2-85): 2.82e-15: 73.8: 21.59		CUL3_HUMAN (1-745): 0: 768: 26.38
+	Hs
		862036 DAPK1_HUMAN (49-155): 4.06e-14: 70.4: 22.02		CUL3_HUMAN (1-745): 0: 768: 26.38
+	Hs
		1043269 RAI14_HUMAN (1-64): 1.97e-11: 62.7: 21.21		CUL4A_HUMAN (4-745): 0: 773: 26.86
+	Hs
		276178 PSD10_HUMAN (1-85): 4.57e-12: 63.1: 23.86		CUL3_HUMAN (1-745): 0: 768: 26.38
+	Hs
		1042160 ASB13_HUMAN (80-147): 2.84e-11: 61.6: 23.53		CUL3_HUMAN (1-745): 0: 768: 26.38
+	Hs
		166925 ANR28_HUMAN (82-155): 3.69e-09: 56.1: 16.22		CUL3_HUMAN (1-745): 0: 768: 26.38
+	Hs
		1264009 ASB15_HUMAN (16-136): 6.7e-42: 148: 33.07		CUL5_HUMAN (7-745): 0: 627: 26.69
+	Hs
		1274049 ASB8_HUMAN (60-153): 1.29e-19: 84.2: 21.28		CUL5_HUMAN (7-745): 0: 627: 26.69
+	Hs
		1274043 TNKS2_HUMAN (8-136): 1.5e-11: 63.2: 21.05		CUL5_HUMAN (7-745): 0: 627: 26.69
+	Hs
		1264015 ASB13_HUMAN (80-147): 2.84e-11: 61.6: 23.53		CUL5_HUMAN (7-745): 0: 627: 26.69