HitPredict

Interactor 1: CDN2A (P42771)
Cyclin-dependent kinase inhibitor 2A (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (Multiple tumor suppressor 1) (MTS-1) (p16-INK4a) (p16-INK4) (p16INK4A)
Gene: CDKN2A

Interactor 2: TRIPC (Q14669)
E3 ubiquitin-protein ligase TRIP12 (EC 2.3.2.26) (E3 ubiquitin-protein ligase for Arf) (ULF) (HECT-type E3 ubiquitin transferase TRIP12) (Thyroid receptor-interacting protein 12) (TR-interacting protein 12) (TRIP-12)
Gene: TRIP12

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.86	0.60	0.720

Property	Details
Experiments	20208519, 23034180, 27323397, 22561347, 24769896
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 156 Hs			1 1992
+	Hs
		125040 ANR17_HUMAN (69-147): 2.99e-19: 85.1: 20.25		WWP2_HUMAN (1053-1990): 0: 603: 18.31
+	Hs
		125054 PSD10_HUMAN (1-85): 4.57e-12: 63.1: 23.86		WWP2_HUMAN (1053-1990): 0: 603: 18.31
+	Hs
		125583 ANR44_HUMAN (2-76): 4.04e-10: 58.8: 18.99		WWP2_HUMAN (1053-1990): 0: 603: 18.31
+	Hs
		808109 ANK3_HUMAN (15-155): 1.26e-35: 132: 21.13		NEDD4_HUMAN (814-1990): 2.08e-159: 528: 13.49
+	Hs
		1336115 ANR50_HUMAN (26-149): 1.07e-26: 106: 26.61		SMUF1_HUMAN (1455-1989): 1.22e-158: 508: 18.46
+	Hs
		60363 POTEF_HUMAN (1-130): 1.26e-29: 115: 19.55		HACE1_HUMAN (1402-1992): 1.1e-146: 480: 20.23
+	Hs
		1164377 POTEE_HUMAN (49-152): 2.11e-18: 82.7: 14.82		SMUF1_HUMAN (1455-1989): 1.22e-158: 508: 18.46
+	Hs
		60328 POTEF_HUMAN (1-130): 1.26e-29: 115: 19.55		UBE3A_HUMAN (1492-1991): 2.41e-140: 462: 27.02
+	Hs
		276173 PSD10_HUMAN (1-85): 4.57e-12: 63.1: 23.86		UBE3A_HUMAN (1492-1991): 2.41e-140: 462: 27.02
+	Hs
		167039 ANR28_HUMAN (82-155): 3.69e-09: 56.1: 16.22		HECD1_HUMAN (437-1230): 6.18e-77: 287: 15.52
+	Hs
		790814 CDN2A_HUMAN (1-156): 1.38e-51: 163: 100.00		HUWE1_HUMAN (1616-1992): 2.18e-25: 118: 28.72
+	Hs
		1072718 Q9H4D1_HUMAN (9-155): 2.04e-30: 116: 25.68		UBE3C_HUMAN (1697-1992): 3.54e-26: 119: 30.57
+	Hs
		883550 RIPK4_HUMAN (9-155): 1.21e-30: 117: 25.68		HUWE1_HUMAN (1616-1992): 2.18e-25: 118: 28.72
+	Hs
		1192213 Q9H4D1_HUMAN (9-155): 2.04e-30: 116: 25.68		HUWE1_HUMAN (1616-1992): 2.18e-25: 118: 28.72