HitPredict

Interactor 1: CDN2A (P42771)
Cyclin-dependent kinase inhibitor 2A (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (Multiple tumor suppressor 1) (MTS-1) (p16-INK4a) (p16-INK4) (p16INK4A)
Gene: CDKN2A

Interactor 2: H2B3B (Q8N257)
Histone H2B type 3-B (H2B type 12) (H2B-clustered histone 26) (H2B.U histone 1)
Gene: H2BC26

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.561

Property	Details
Experiments	21846774
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 156 Hs			1 126
+	Hs
		1087410 EHMT1_HUMAN (4-121): 1.19e-30: 117: 19.33		H2B2E_HUMAN (1-126): 9.44e-55: 168: 96.03
+	Hs
		918699 EHMT1_HUMAN (4-121): 1.19e-30: 117: 19.33		H2B1C_HUMAN (1-126): 1.76e-54: 168: 95.24
+	Hs
		1087341 EHMT2_HUMAN (4-114): 3.84e-29: 113: 24.11		H2B2E_HUMAN (1-126): 9.44e-55: 168: 96.03
+	Hs
		918611 EHMT2_HUMAN (4-114): 3.84e-29: 113: 24.11		H2B1C_HUMAN (1-126): 1.76e-54: 168: 95.24
+	Hs
		1231227 EHMT2_HUMAN (4-114): 3.84e-29: 113: 24.11		H2B3B_HUMAN (1-126): 1.04e-52: 163: 100.00
+	Hs
		1282965 EHMT1_HUMAN (4-121): 1.19e-30: 117: 19.33		H2B1A_HUMAN (1-126): 3.85e-47: 149: 85.83
+	Hs
		1282945 EHMT2_HUMAN (4-114): 3.84e-29: 113: 24.11		H2B1A_HUMAN (1-126): 3.85e-47: 149: 85.83
+	Hs
		918457 POTEE_HUMAN (49-152): 2.11e-18: 82.7: 14.82		H2B1C_HUMAN (1-126): 1.76e-54: 168: 95.24
+	Hs
		862088 DAPK1_HUMAN (49-155): 4.06e-14: 70.4: 22.02		H2B1H_HUMAN (1-126): 5.83e-55: 169: 96.03
+	Hs
		276167 PSD10_HUMAN (1-85): 4.57e-12: 63.1: 23.86		H2B1C_HUMAN (1-126): 1.76e-54: 168: 95.24