HitPredict

Interactor 1: CDN2C (P42773)
Cyclin-dependent kinase 4 inhibitor C (Cyclin-dependent kinase 6 inhibitor) (p18-INK4c) (p18-INK6)
Gene: CDKN2C

Interactor 2: ANR44 (Q8N8A2)
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B (PP6-ARS-B) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-B) (Ankyrin repeat domain-containing protein 44)
Gene: ANKRD44

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.80	0.770

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ank~Ank_2, Ank_2~Ank_2, Ank_2~Ank_4, Ank~Ank_4, Ank_4~Ank_4
Common GO terms	-
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 168 Hs			1 993
+	Mm
		970499 ANS1B_MOUSE (59-156): 6.92e-16: 75.9: 37.00		ANK1_MOUSE (208-991): 4.3e-179: 569: 29.99
+	Hs
		1349604 RAI14_HUMAN (1-135): 3.41e-37: 136: 21.32		ANR50_HUMAN (1-397): 1.15e-102: 353: 27.36
+	Hs
		883496 RIPK4_HUMAN (1-99): 1.47e-26: 106: 28.00		ANK3_HUMAN (572-992): 6.43e-99: 345: 26.61
+	Hs
		1350525 KDIS_HUMAN (2-159): 8.8e-46: 161: 26.42		ANFY1_HUMAN (2-536): 1.38e-78: 281: 19.57
+	Mm
		103591 ANK3_MOUSE (77-168): 6.89e-24: 98.8: 42.39		ANK3_MOUSE (572-992): 6.57e-95: 333: 26.39
+	Hs
		862028 DAPK1_HUMAN (42-168): 1.97e-29: 114: 20.93		ANK2_HUMAN (630-987): 2.82e-89: 316: 25.55
+	Hs
		965160 TANC2_HUMAN (17-164): 6.3e-27: 107: 22.50		ANK2_HUMAN (630-987): 2.82e-89: 316: 25.55
+	Hs
		883487 RIPK4_HUMAN (1-99): 1.47e-26: 106: 28.00		ANK2_HUMAN (630-987): 2.82e-89: 316: 25.55
+	Mm
		103608 ANK3_MOUSE (77-168): 6.89e-24: 98.8: 42.39		ANK2_MOUSE (630-987): 4.52e-88: 313: 25.55
+	Dr
		47649 A0AR23_DANRE (9-137): 7.85e-15: 72.8: 34.62		ANR52_DANRE (595-993): 5.45e-72: 261: 26.50
+	Hs
		166998 EHMT2_HUMAN (3-143): 9.16e-45: 158: 34.27		ANR28_HUMAN (1-148): 9.57e-21: 100: 23.24
+	Hs
		257652 ANR17_HUMAN (3-166): 2.37e-18: 83: 20.10		ANKH1_HUMAN (693-992): 4.95e-42: 170: 21.82
+	Hs
		167036 ANR50_HUMAN (51-168): 3.96e-26: 105: 28.81		ANR28_HUMAN (1-148): 9.57e-21: 100: 23.24
+	Hs
		166919 ANK3_HUMAN (77-168): 3.08e-25: 103: 41.30		ANR28_HUMAN (1-148): 9.57e-21: 100: 23.24
+	Hs
		166913 ANK2_HUMAN (77-168): 1.26e-23: 98.4: 40.22		ANR28_HUMAN (1-148): 9.57e-21: 100: 23.24
+	Hs
		166971 ANR52_HUMAN (9-161): 7.78e-09: 55.5: 33.55		ANR28_HUMAN (1-148): 9.57e-21: 100: 23.24