Interactor 1: SYUA (P37840)
Alpha-synuclein (Non-A beta component of AD amyloid) (Non-A4 component of amyloid precursor) (NACP)
Gene: SNCA
Interactor 2: SYUA (P37840)
Alpha-synuclein (Non-A beta component of AD amyloid) (Non-A4 component of amyloid precursor) (NACP)
Gene: SNCA
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.99 | 1.00 | 0.996 |
The method score is based on:
Property | Details |
---|---|
Experiments | 25484190, 25617759, 27341336, 25555914, 25058424, 31980649, 31270237, 32430178, 33444530, 34408321, 36634849, 37242709, 39079530, 18221373, 21358815, 19651786, 20849899, 11502187, 18179253, 18505736 and 22 others
more... |
Identification Methods | pull down, biochemical, affinity chromatography technology, protein complementation assay, proximity labelling technology, two hybrid, fluorescent resonance energy transfer, bimolecular fluorescence complementation, comigration in sds page, electron microscopy and 23 others
more... |
Interaction Type | direct interaction, association, physical association |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | Synuclein~Synuclein |
Common GO terms | GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000149 - SNARE binding GO:0000287 - magnesium ion binding GO:0000976 - transcription cis-regulatory region binding GO:0001774 - microglial cell activation and 121 others more... |
Homologous interactions | 3 |
Service provided by Combinatics, Japan
Last updated: 11Aug2025