Interactor 1: LEM3 (P42838)
Phospholipid-transporting ATPase accessory subunit LEM3 (Alkylphosphocholine resistance protein LEM3) (Brefeldin-A sensitivity protein 3) (Ro-sensitive 3)
Gene: LEM3

Interactor 2: ATC4 (Q12675)
Phospholipid-transporting ATPase DNF2 (EC 7.6.2.1) (Flippase DNF2)
Gene: DNF2

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.89 1.00 0.944

The method score is based on:

Property Details
Experiments 33320091, 17093059, 16600184, 18467557, 37968396, 23060447
Identification Methods biochemical, x-ray crystallography, affinity chromatography technology, protein complementation assay, anti bait coimmunoprecipitation, dihydrofolate reductase reconstruction
Interaction Type association, physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains CDC50~PhoLip_ATPase_C, CDC50~PhoLip_ATPase_N
Common GO terms GO:0005783 - endoplasmic reticulum
GO:0005886 - plasma membrane
GO:0045332 - phospholipid translocation
GO:1990531 - phospholipid-translocating ATPase complex
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 414
Sc

1 1612
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Last updated: 15 Jul 2024