Interactor 1: HD (P42858)
Huntingtin (Huntington disease protein) (HD protein) [Cleaved into: Huntingtin, myristoylated N-terminal fragment]
Gene: HTT

Interactor 2: DYN2 (P50570)
Dynamin-2 (EC 3.6.5.5) (Dynamin 2) (Dynamin II)
Gene: DNM2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.59 0.60 0.596

The method score is based on:

Property Details
Experiments 32814053, 17500595
Identification Methods two hybrid array, two hybrid pooling approach, validated two hybrid, two hybrid
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0005794 - Golgi apparatus
GO:0005814 - centriole
GO:0005829 - cytosol
GO:0043065 - positive regulation of apoptotic process
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 3142
Hs

1 870
+ Hs
+ Mm
+ Mm
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024