HitPredict

Interactor 1: HD (P42858)
Huntingtin (Huntington disease protein) (HD protein) [Cleaved into: Huntingtin, myristoylated N-terminal fragment]
Gene: HTT

Interactor 2: TBA1A (Q71U36)
Tubulin alpha-1A chain (EC 3.6.5.-) (Alpha-tubulin 3) (Tubulin B-alpha-1) (Tubulin alpha-3 chain) [Cleaved into: Detyrosinated tubulin alpha-1A chain]
Gene: TUBA1A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	12417652, 32814053
Identification Methods	affinity chromatography technology, two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 3142 Hs			1 451
+	Hs
		428074 HD_HUMAN (1-3142): 0: 5724: 100.00		TBB5_HUMAN (1-439): 0: 695: 40.77
+	Mm
		102738 G3X9H5_MOUSE (81-3142): 0: 5479: 91.19		TBA1B_MOUSE (1-440): 0: 715: 99.55
+	Mm
		102963 G3X9H5_MOUSE (81-3142): 0: 5479: 91.19		TBA1A_MOUSE (1-440): 0: 713: 100.00
+	Mm
		102739 G3X9H5_MOUSE (81-3142): 0: 5479: 91.19		TBA3_MOUSE (1-440): 0: 710: 98.18
+	Mm
		103250 G3X9H5_MOUSE (81-3142): 0: 5479: 91.19		TBA8_MOUSE (1-440): 0: 702: 90.91
+	Rn
		102589 G3V9P7_RAT (81-3142): 0: 5407: 91.19		TBB5_RAT (1-439): 0: 695: 40.77